Martin Friedlander Selected Research

Telangiectasis (Telangiectasia)

1/2022	Description of a patient cohort with Hereditary Sensory Neuropathy type 1 without retinal disease Macular Telangiectasia type 2 - implications for retinal screening in HSN1.
1/2022	Deep learning-based classification and segmentation of retinal cavitations on optical coherence tomography images of macular telangiectasia type 2.
1/2021	Toxicity Screens in Human Retinal Organoids for Pharmaceutical Discovery.
1/2021	Serine biosynthesis defect due to haploinsufficiency of PHGDH causes retinal disease.
1/2021	Optical coherence tomography-angiography for monitoring neovascularisations in macular telangiectasia type 2.
1/2020	CNTF Prevents Development of Outer Retinal Neovascularization Through Upregulation of CxCl10.
1/2020	Retinal microglia are critical for subretinal neovascular formation.
10/2019	Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy.
1/2019	Effect of Ciliary Neurotrophic Factor on Retinal Neurodegeneration in Patients with Macular Telangiectasia Type 2: A Randomized Clinical Trial.
1/2017	Correlation Between Macular Integrity Assessment and Optical Coherence Tomography Imaging of Ellipsoid Zone in Macular Telangiectasia Type 2.

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Martin Friedlander Research Topics

Disease

13	Telangiectasis (Telangiectasia) 01/2022 - 03/2009
11	Retinal Diseases 01/2022 - 01/2005
11	Hypoxia (Hypoxemia) 01/2022 - 12/2006
9	Neoplasms (Cancer) 11/2016 - 05/2002
7	Pathologic Neovascularization 01/2022 - 11/2002
6	Retinal Neovascularization 01/2022 - 04/2002
6	Retinal Degeneration 01/2019 - 09/2004
6	Macular Degeneration (Age-Related Maculopathy) 01/2017 - 09/2005
5	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 09/2010
5	Eye Diseases (Eye Disease) 01/2014 - 01/2007
3	Ischemia 01/2022 - 12/2017
3	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2016 - 09/2005
3	Vascular Diseases (Vascular Disease) 01/2016 - 06/2008
3	Hemorrhage 03/2009 - 01/2007
2	Papilledema 06/2008 - 01/2007
2	Hemangioma (Angioma) 01/2003 - 05/2002
1	Hereditary Sensory and Autonomic Neuropathies (HSAN) 01/2022
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2022
1	Leukostasis 01/2022
1	Choroidal Neovascularization 01/2020
1	Peripheral Nervous System Diseases (PNS Diseases) 10/2019
1	Vision Disorders (Hemeralopia) 10/2019
1	Muscular Dystrophies (Muscular Dystrophy) 10/2019
1	Thrombotic Microangiopathies 01/2017
1	Optic Nerve Diseases (Optic Neuropathy) 01/2017
1	Teratoma (Teratoid Tumor) 09/2015
1	Necrosis 09/2015
1	Optic Atrophy 06/2015
1	Wolfram Syndrome (Syndrome, Wolfram) 06/2015
1	Hypertension (High Blood Pressure) 12/2010
1	Hyperoxia 06/2007
1	Hypertrophy 05/2007
1	Heart Failure 05/2007
1	Fibrosis (Cirrhosis) 03/2007
1	Gliosarcoma 01/2007
1	Retinal Detachment (Retinal Detachments) 01/2007
1	Vitreous Hemorrhage 01/2007
1	Vascular Remodeling 05/2006
1	Retinal Vein Occlusion 09/2005
1	Atrophy 09/2004
1	Infections 01/2003

Drug/Important Bio-Agent (IBA)

32	Retinaldehyde (Retinal)IBA 01/2022 - 11/2002
11	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2020 - 05/2006
9	Oxygen (Dioxygen)IBA 01/2022 - 09/2005
3	Serine (L-Serine)FDA Link 01/2022 - 10/2019
3	Ciliary Neurotrophic Factor (CNTF)IBA 01/2020 - 01/2016
3	Proteins (Proteins, Gene)FDA Link 08/2010 - 05/2002
2	Transcription Factors (Transcription Factor)IBA 11/2020 - 08/2010
2	LipidsIBA 01/2020 - 04/2016
2	Nerve Growth Factors (Neurotrophins)IBA 01/2020 - 01/2016
2	DNA (Deoxyribonucleic Acid)IBA 01/2003 - 05/2002
2	Insulin-Like PeptidesIBA 01/2003 - 05/2002
1	Tamoxifen FDA LinkGeneric 01/2022
1	TransferasesIBA 01/2022
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2022
1	CeramidesIBA 01/2021
1	Pharmaceutical PreparationsIBA 01/2021
1	InterferonsIBA 01/2021
1	Peptides (Polypeptides)IBA 11/2020
1	Peptide FragmentsIBA 11/2020
1	Serine C-PalmitoyltransferaseIBA 10/2019
1	Amino Acids FDA Link 10/2019
1	DystrophinIBA 10/2019
1	Neuroprotective AgentsIBA 01/2019
1	salicylhydroxamic acid (SHAM)IBA 01/2019
1	Coloring Agents (Dyes)IBA 11/2016
1	Amyloid (Amyloid Fibrils)IBA 10/2016
1	Glucose (Dextrose)FDA LinkGeneric 04/2016
1	Arginine (L-Arginine)FDA Link 01/2016
1	Retinal Pigments (Pigments, Visual)IBA 01/2016
1	Proline (L-Proline)FDA Link 01/2016
1	AntigensIBA 09/2015
1	Insulin (Novolin)FDA Link 06/2015
1	Macular PigmentIBA 12/2010
1	endothelial PAS domain-containing protein 1IBA 08/2010
1	src-Family KinasesIBA 06/2008
1	PAR-1 ReceptorIBA 06/2007
1	CalciumIBA 05/2007
1	Adrenergic Agents (Adrenergic Drugs)IBA 05/2007
1	Sodium-Calcium ExchangerIBA 05/2007
1	Biological ProductsIBA 03/2007
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 05/2006
1	Integrin alpha4beta1 (VLA-4)IBA 03/2006
1	erucylphosphocholineIBA 01/2005
1	Thromboplastin (Tissue Factor)IBA 05/2004
1	Peptide Hydrolases (Proteases)FDA Link 05/2004
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 01/2003
1	hypoiodous acid (HOI)IBA 01/2003
1	Integrin alpha ChainsIBA 05/2002
1	Insulin-Like Growth Factor II (Somatomedin A)IBA 05/2002
1	IntegrinsIBA 04/2002
1	Integrin alphaVIBA 04/2002

Therapy/Procedure

15	Therapeutics 01/2021 - 09/2005
2	Intravitreal Injections 01/2020 - 01/2007
2	Transplantation 10/2016 - 02/2012
2	Intraocular Injections 06/2008 - 01/2003
1	Lasers (Laser) 01/2020
1	Glycemic Control 06/2015
1	Traction 01/2007